RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade

BACKGROUND: Antibody-mediated targeting of regulatory T cell receptors such as CTLA-4 enhances antitumor immune responses against several cancer entities including malignant melanoma. Yet, therapeutic success in patients remains variable underscoring the need for novel combinatorial approaches. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Heidegger, Simon, Kreppel, Diana, Bscheider, Michael, Stritzke, Florian, Nedelko, Tatiana, Wintges, Alexander, Bek, Sarah, Fischer, Julius C., Graalmann, Theresa, Kalinke, Ulrich, Bassermann, Florian, Haas, Tobias, Poeck, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444128/
https://www.ncbi.nlm.nih.gov/pubmed/30852164
http://dx.doi.org/10.1016/j.ebiom.2019.02.056

Ejemplares similares

Ejemplares similares