Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination

Rhinogenic headache is frequently encountered in clinical practice. Treatment of this condition should be based on a proper evaluation of its underlying pathophysiology. Fixed-dose combinations of two or more active agents, and specifically the combination of ibuprofen plus pseudoephedrine, have bee...

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Detalles Bibliográficos
Autores principales: CHIARUGI, A., CAMAIONI, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2019
Materias:
Rhinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444167/
https://www.ncbi.nlm.nih.gov/pubmed/30936575
http://dx.doi.org/10.14639/0392-100X-1882
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author CHIARUGI, A.
CAMAIONI, A.
author_facet CHIARUGI, A.
CAMAIONI, A.
author_sort CHIARUGI, A.
collection PubMed
description Rhinogenic headache is frequently encountered in clinical practice. Treatment of this condition should be based on a proper evaluation of its underlying pathophysiology. Fixed-dose combinations of two or more active agents, and specifically the combination of ibuprofen plus pseudoephedrine, have been shown to be more efficacious than either monotherapy. At present, an ibuprofen/pseudoephedrine fixed-dose combination is available as an over-the-counter drug. This paper reviews in detail the pathophysiology of rhinogenic headache and discusses the rationale for treatment of this condition with a fixed-dose ibuprofen/pseudoephedrine combination.
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spelling pubmed-64441672019-04-03 Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination CHIARUGI, A. CAMAIONI, A. Acta Otorhinolaryngol Ital Rhinology Rhinogenic headache is frequently encountered in clinical practice. Treatment of this condition should be based on a proper evaluation of its underlying pathophysiology. Fixed-dose combinations of two or more active agents, and specifically the combination of ibuprofen plus pseudoephedrine, have been shown to be more efficacious than either monotherapy. At present, an ibuprofen/pseudoephedrine fixed-dose combination is available as an over-the-counter drug. This paper reviews in detail the pathophysiology of rhinogenic headache and discusses the rationale for treatment of this condition with a fixed-dose ibuprofen/pseudoephedrine combination. Pacini Editore Srl 2019-02 /pmc/articles/PMC6444167/ /pubmed/30936575 http://dx.doi.org/10.14639/0392-100X-1882 Text en Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way. For details, please refer to https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Rhinology
CHIARUGI, A.
CAMAIONI, A.
Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title_full Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title_fullStr Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title_full_unstemmed Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title_short Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
title_sort update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination
topic Rhinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444167/
https://www.ncbi.nlm.nih.gov/pubmed/30936575
http://dx.doi.org/10.14639/0392-100X-1882
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