Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a late onset neurodegenerative disease with fast progression. ALS has heavy genetic components in which a series of genetic mutations have been identified. In 2013, Mutations of the CREST gene (also known as SS18L1), which functions as a calcium-reg...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Yang, Kan, Wu, Xinwei, Zhang, Yuefang, Shan, Shifang, Gitler, Aaron, Ghosh, Anirvan, Qiu, Zilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444434/
https://www.ncbi.nlm.nih.gov/pubmed/30976389
http://dx.doi.org/10.1186/s40035-019-0152-1

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