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An improved synthesis of adefovir and related analogues

An improved synthesis of the antiviral drug adefovir is presented. Problems associated with current routes to adefovir include capricious yields and a reliance on problematic reagents and solvents, such as magnesium tert-butoxide and DMF, to achieve high conversions to the target. A systematic study...

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Detalles Bibliográficos
Autores principales:	Jones, David J, O’Leary, Eileen M, O’Sullivan, Timothy P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2019
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444443/ https://www.ncbi.nlm.nih.gov/pubmed/30992729 http://dx.doi.org/10.3762/bjoc.15.77

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