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Microneedle – Future prospect for efficient drug delivery in diabetes management

This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other si...

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Detalles Bibliográficos
Autores principales: Jana, Baishali A., Wadhwani, Ashish D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444834/
https://www.ncbi.nlm.nih.gov/pubmed/31031461
http://dx.doi.org/10.4103/ijp.IJP_16_18
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author Jana, Baishali A.
Wadhwani, Ashish D.
author_facet Jana, Baishali A.
Wadhwani, Ashish D.
author_sort Jana, Baishali A.
collection PubMed
description This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other side effects. Hence, this drug delivery research has found to have tremendous potential in combining both the diagnostic and therapeutic elements, thus treating diabetes in a better way. Most glucose-sensing techniques and conventional insulin therapies are engaged in the transfer of physical entities through the skin. MN- based drug delivery system can accomplish in an noninvasive or minimally invasive manner which can be an add on advantage towards pain-free administration, easy handling, discrete, continuous as well as providing a controlled release system. Hence, the review addresses on the current advancement of this bioengineered system like MNs, constituting a “smart” system specifically for autonomous diabetes therapy.
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spelling pubmed-64448342019-04-26 Microneedle – Future prospect for efficient drug delivery in diabetes management Jana, Baishali A. Wadhwani, Ashish D. Indian J Pharmacol Review Article This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other side effects. Hence, this drug delivery research has found to have tremendous potential in combining both the diagnostic and therapeutic elements, thus treating diabetes in a better way. Most glucose-sensing techniques and conventional insulin therapies are engaged in the transfer of physical entities through the skin. MN- based drug delivery system can accomplish in an noninvasive or minimally invasive manner which can be an add on advantage towards pain-free administration, easy handling, discrete, continuous as well as providing a controlled release system. Hence, the review addresses on the current advancement of this bioengineered system like MNs, constituting a “smart” system specifically for autonomous diabetes therapy. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6444834/ /pubmed/31031461 http://dx.doi.org/10.4103/ijp.IJP_16_18 Text en Copyright: © 2019 Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Jana, Baishali A.
Wadhwani, Ashish D.
Microneedle – Future prospect for efficient drug delivery in diabetes management
title Microneedle – Future prospect for efficient drug delivery in diabetes management
title_full Microneedle – Future prospect for efficient drug delivery in diabetes management
title_fullStr Microneedle – Future prospect for efficient drug delivery in diabetes management
title_full_unstemmed Microneedle – Future prospect for efficient drug delivery in diabetes management
title_short Microneedle – Future prospect for efficient drug delivery in diabetes management
title_sort microneedle – future prospect for efficient drug delivery in diabetes management
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444834/
https://www.ncbi.nlm.nih.gov/pubmed/31031461
http://dx.doi.org/10.4103/ijp.IJP_16_18
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