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Microneedle – Future prospect for efficient drug delivery in diabetes management
This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other si...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444834/ https://www.ncbi.nlm.nih.gov/pubmed/31031461 http://dx.doi.org/10.4103/ijp.IJP_16_18 |
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author | Jana, Baishali A. Wadhwani, Ashish D. |
author_facet | Jana, Baishali A. Wadhwani, Ashish D. |
author_sort | Jana, Baishali A. |
collection | PubMed |
description | This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other side effects. Hence, this drug delivery research has found to have tremendous potential in combining both the diagnostic and therapeutic elements, thus treating diabetes in a better way. Most glucose-sensing techniques and conventional insulin therapies are engaged in the transfer of physical entities through the skin. MN- based drug delivery system can accomplish in an noninvasive or minimally invasive manner which can be an add on advantage towards pain-free administration, easy handling, discrete, continuous as well as providing a controlled release system. Hence, the review addresses on the current advancement of this bioengineered system like MNs, constituting a “smart” system specifically for autonomous diabetes therapy. |
format | Online Article Text |
id | pubmed-6444834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-64448342019-04-26 Microneedle – Future prospect for efficient drug delivery in diabetes management Jana, Baishali A. Wadhwani, Ashish D. Indian J Pharmacol Review Article This review aims at focusing on the use of microneedles (MNs) as an emerging novel drug delivery carrier for an effective treatment in diabetic patients. There are many limitations in various modes of delivery such as oral, subcutaneous, nasal, and other modes which cause pain and have many other side effects. Hence, this drug delivery research has found to have tremendous potential in combining both the diagnostic and therapeutic elements, thus treating diabetes in a better way. Most glucose-sensing techniques and conventional insulin therapies are engaged in the transfer of physical entities through the skin. MN- based drug delivery system can accomplish in an noninvasive or minimally invasive manner which can be an add on advantage towards pain-free administration, easy handling, discrete, continuous as well as providing a controlled release system. Hence, the review addresses on the current advancement of this bioengineered system like MNs, constituting a “smart” system specifically for autonomous diabetes therapy. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6444834/ /pubmed/31031461 http://dx.doi.org/10.4103/ijp.IJP_16_18 Text en Copyright: © 2019 Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Jana, Baishali A. Wadhwani, Ashish D. Microneedle – Future prospect for efficient drug delivery in diabetes management |
title | Microneedle – Future prospect for efficient drug delivery in diabetes management |
title_full | Microneedle – Future prospect for efficient drug delivery in diabetes management |
title_fullStr | Microneedle – Future prospect for efficient drug delivery in diabetes management |
title_full_unstemmed | Microneedle – Future prospect for efficient drug delivery in diabetes management |
title_short | Microneedle – Future prospect for efficient drug delivery in diabetes management |
title_sort | microneedle – future prospect for efficient drug delivery in diabetes management |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444834/ https://www.ncbi.nlm.nih.gov/pubmed/31031461 http://dx.doi.org/10.4103/ijp.IJP_16_18 |
work_keys_str_mv | AT janabaishalia microneedlefutureprospectforefficientdrugdeliveryindiabetesmanagement AT wadhwaniashishd microneedlefutureprospectforefficientdrugdeliveryindiabetesmanagement |