Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease

BACKGROUND: Macrophages engulf oxidized-LDL (oxLDL) leading to accumulation of cellular cholesterol and formation of foam cells, which is a hallmark of atherosclerosis. Moreover, recent studies showed that accumulation of free cholesterol in macrophages leading to activation of NLRP3 inflammasome an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Cheng-Maw, Ho, Shu-Li, Jeng, Yung-Ming, Lai, Yu-Sheng, Chen, Ya-Hui, Lu, Shao-Chun, Chen, Hui-Ling, Chang, Po-Yuan, Hu, Rey-Heng, Lee, Po-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444889/
https://www.ncbi.nlm.nih.gov/pubmed/30983887
http://dx.doi.org/10.1186/s12950-019-0211-5

Ejemplares similares

Ejemplares similares