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Multimodal epidermal devices for hydration monitoring

Precise, quantitative in vivo monitoring of hydration levels in the near surface regions of the skin can be useful in preventing skin-based pathologies, and regulating external appearance. Here we introduce multimodal sensors with important capabilities in this context, rendered in soft, ultrathin,...

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Autores principales: Krishnan, Siddharth, Shi, Yunzhou, Webb, R. Chad, Ma, Yinji, Bastien, Philippe, Crawford, Kaitlyn E., Wang, Ao, Feng, Xue, Manco, Megan, Kurniawan, Jonas, Tir, Edward, Huang, Yonggang, Balooch, Guive, Pielak, Rafal M., Rogers, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444991/
https://www.ncbi.nlm.nih.gov/pubmed/31057861
http://dx.doi.org/10.1038/micronano.2017.14
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author Krishnan, Siddharth
Shi, Yunzhou
Webb, R. Chad
Ma, Yinji
Bastien, Philippe
Crawford, Kaitlyn E.
Wang, Ao
Feng, Xue
Manco, Megan
Kurniawan, Jonas
Tir, Edward
Huang, Yonggang
Balooch, Guive
Pielak, Rafal M.
Rogers, John A.
author_facet Krishnan, Siddharth
Shi, Yunzhou
Webb, R. Chad
Ma, Yinji
Bastien, Philippe
Crawford, Kaitlyn E.
Wang, Ao
Feng, Xue
Manco, Megan
Kurniawan, Jonas
Tir, Edward
Huang, Yonggang
Balooch, Guive
Pielak, Rafal M.
Rogers, John A.
author_sort Krishnan, Siddharth
collection PubMed
description Precise, quantitative in vivo monitoring of hydration levels in the near surface regions of the skin can be useful in preventing skin-based pathologies, and regulating external appearance. Here we introduce multimodal sensors with important capabilities in this context, rendered in soft, ultrathin, ‘skin-like’ formats with numerous advantages over alternative technologies, including the ability to establish intimate, conformal contact without applied pressure, and to provide spatiotemporally resolved data on both electrical and thermal transport properties from sensitive regions of the skin. Systematic in vitro studies and computational models establish the underlying measurement principles and associated approaches for determination of temperature, thermal conductivity, thermal diffusivity, volumetric heat capacity, and electrical impedance using simple analysis algorithms. Clinical studies on 20 patients subjected to a variety of external stimuli validate the device operation and allow quantitative comparisons of measurement capabilities to those of existing state-of-the-art tools.
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spelling pubmed-64449912019-05-03 Multimodal epidermal devices for hydration monitoring Krishnan, Siddharth Shi, Yunzhou Webb, R. Chad Ma, Yinji Bastien, Philippe Crawford, Kaitlyn E. Wang, Ao Feng, Xue Manco, Megan Kurniawan, Jonas Tir, Edward Huang, Yonggang Balooch, Guive Pielak, Rafal M. Rogers, John A. Microsyst Nanoeng Article Precise, quantitative in vivo monitoring of hydration levels in the near surface regions of the skin can be useful in preventing skin-based pathologies, and regulating external appearance. Here we introduce multimodal sensors with important capabilities in this context, rendered in soft, ultrathin, ‘skin-like’ formats with numerous advantages over alternative technologies, including the ability to establish intimate, conformal contact without applied pressure, and to provide spatiotemporally resolved data on both electrical and thermal transport properties from sensitive regions of the skin. Systematic in vitro studies and computational models establish the underlying measurement principles and associated approaches for determination of temperature, thermal conductivity, thermal diffusivity, volumetric heat capacity, and electrical impedance using simple analysis algorithms. Clinical studies on 20 patients subjected to a variety of external stimuli validate the device operation and allow quantitative comparisons of measurement capabilities to those of existing state-of-the-art tools. Nature Publishing Group 2017-06-05 /pmc/articles/PMC6444991/ /pubmed/31057861 http://dx.doi.org/10.1038/micronano.2017.14 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Krishnan, Siddharth
Shi, Yunzhou
Webb, R. Chad
Ma, Yinji
Bastien, Philippe
Crawford, Kaitlyn E.
Wang, Ao
Feng, Xue
Manco, Megan
Kurniawan, Jonas
Tir, Edward
Huang, Yonggang
Balooch, Guive
Pielak, Rafal M.
Rogers, John A.
Multimodal epidermal devices for hydration monitoring
title Multimodal epidermal devices for hydration monitoring
title_full Multimodal epidermal devices for hydration monitoring
title_fullStr Multimodal epidermal devices for hydration monitoring
title_full_unstemmed Multimodal epidermal devices for hydration monitoring
title_short Multimodal epidermal devices for hydration monitoring
title_sort multimodal epidermal devices for hydration monitoring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444991/
https://www.ncbi.nlm.nih.gov/pubmed/31057861
http://dx.doi.org/10.1038/micronano.2017.14
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