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Co-regulated gene expression of splicing factors as drivers of cancer progression

Splicing factors (SFs) act in dynamic macromolecular complexes to modulate RNA processing. To understand the complex role of SFs in cancer progression, we performed a systemic analysis of the co-regulation of SFs using primary tumor RNA sequencing data. Co-regulated SFs were associated with aggressi...

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Detalles Bibliográficos
Autores principales:	Koedoot, Esmee, Smid, Marcel, Foekens, John A., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445126/ https://www.ncbi.nlm.nih.gov/pubmed/30940821 http://dx.doi.org/10.1038/s41598-019-40759-4

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