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Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules
Oral mucositis (OM) is one of the main side effects of the head and neck cancer treatment, particularly radiotherapy and/or chemotherapy. OM is characterized by ulcers, erythema, dysphagia, xerostomia, and increased susceptibility to opportunistic infections. In the perspective of finding pharmacolo...
Autores principales: | Mafra, Cristiane Assunção da Costa Cunha, Vasconcelos, Roseane Carvalho, de Medeiros, Caroline Addison Carvalho Xavier, Leitão, Renata Ferreira de Carvalho, Brito, Gerly Anne de Castro, Costa, Deiziane Viana da Silva, Guerra, Gerlane Coelho Bernardo, de Araújo, Raimundo Fernandes, Medeiros, Aldo Cunha, de Araújo, Aurigena Antunes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445135/ https://www.ncbi.nlm.nih.gov/pubmed/30971955 http://dx.doi.org/10.3389/fphys.2019.00327 |
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