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β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis
Inhibition of novel biological pathways in Mycobacterium tuberculosis (Mtb) creates the potential for alternative approaches for treating drug-resistant tuberculosis. In vitro studies have shown that dithiocarbamate-derived β-carbonic anhydrase (β-CA) inhibitors Fc14–594 A and Fc14–584B effectively...
Autores principales: | Aspatwar, Ashok, Hammarén, Milka, Koskinen, Sanni, Luukinen, Bruno, Barker, Harlan, Carta, Fabrizio, Supuran, Claudiu T., Parikka, Mataleena, Parkkila, Seppo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445161/ https://www.ncbi.nlm.nih.gov/pubmed/28629306 http://dx.doi.org/10.1080/14756366.2017.1332056 |
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