Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A(2A) receptor

The development of adenosine A(2A) receptor antagonists has received much interest in recent years for the treatment of neurodegenerative diseases. Based on docking studies, a new series of 2-arylbenzoxazoles has been identified as potential A(2A)R antagonists. Structure-affinity relationship was in...

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Detalles Bibliográficos
Autores principales: Duroux, Romain, Renault, Nicolas, Cuelho, Joana Esteves, Agouridas, Laurence, Blum, David, Lopes, Luisa V., Melnyk, Patricia, Yous, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445171/
https://www.ncbi.nlm.nih.gov/pubmed/28661196
http://dx.doi.org/10.1080/14756366.2017.1334648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445171/
https://www.ncbi.nlm.nih.gov/pubmed/28661196
http://dx.doi.org/10.1080/14756366.2017.1334648

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