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Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A(2A) receptor
The development of adenosine A(2A) receptor antagonists has received much interest in recent years for the treatment of neurodegenerative diseases. Based on docking studies, a new series of 2-arylbenzoxazoles has been identified as potential A(2A)R antagonists. Structure-affinity relationship was in...
Autores principales: | Duroux, Romain, Renault, Nicolas, Cuelho, Joana Esteves, Agouridas, Laurence, Blum, David, Lopes, Luisa V., Melnyk, Patricia, Yous, Saïd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445171/ https://www.ncbi.nlm.nih.gov/pubmed/28661196 http://dx.doi.org/10.1080/14756366.2017.1334648 |
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