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SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism
BACKGROUND: SIRT4, a protein localized in the mitochondria, is one of the least characteristic members of the sirtuin family. It is known that SIRT4 has deacetylase activity and plays a role in energy metabolism, but little is known about its possible role in carcinogenesis. Recently, several studie...
Autores principales: | Chen, Zhouxun, Lin, Jiahao, Feng, Shuyi, Chen, Xuxu, Huang, Hanzhang, Wang, Chen, Yu, Yujun, He, Yu, Han, Shaoliang, Zheng, Linfeng, Huang, Guoyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445187/ https://www.ncbi.nlm.nih.gov/pubmed/30992675 http://dx.doi.org/10.2147/OTT.S189536 |
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