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Blocking VEGF by Bevacizumab Compromises Electrophysiological and Morphological Properties of Hippocampal Neurons

A hallmark of glioblastoma multiforme (GBM) is neoangiogenesis, mediated by the overexpression of vascular endothelial growth factor (VEGF). Anti-VEGF antibodies, like bevacizumab, prolong progression-free survival in GBM, however, this treatment has been reported to be associated with a decline in...

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Detalles Bibliográficos
Autores principales:	Latzer, Pauline, Shchyglo, Olena, Hartl, Tim, Matschke, Veronika, Schlegel, Uwe, Manahan-Vaughan, Denise, Theiss, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445260/ https://www.ncbi.nlm.nih.gov/pubmed/30971896 http://dx.doi.org/10.3389/fncel.2019.00113

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