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MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor
In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic re...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445282/ https://www.ncbi.nlm.nih.gov/pubmed/30940837 http://dx.doi.org/10.1038/s41598-019-41892-w |
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author | Abunahla, Heba Mohammad, Baker Alazzam, Anas Jaoude, Maguy Abi Al-Qutayri, Mahmoud Abdul Hadi, Sabina Al-Sarawi, Said F. |
author_facet | Abunahla, Heba Mohammad, Baker Alazzam, Anas Jaoude, Maguy Abi Al-Qutayri, Mahmoud Abdul Hadi, Sabina Al-Sarawi, Said F. |
author_sort | Abunahla, Heba |
collection | PubMed |
description | In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic reservoir for glucose oxidation. The sensor has a linear sensing range between 2.2 mM and 10 mM of glucose concentration, which covers the blood glucose levels for an adult human. The distinguishing property of this sensor is its ability to measure glucose at neutral pH conditions (i.e. pH = 7). Furthermore, the dilution step commonly needed for CuO-based nonenzymatic electrochemical sensors to achieve an alkaline medium, which is essential to perform redox reactions in the absence of glucose oxidase, is eliminated, resulting in a lower-cost and more compact device. |
format | Online Article Text |
id | pubmed-6445282 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-64452822019-04-05 MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor Abunahla, Heba Mohammad, Baker Alazzam, Anas Jaoude, Maguy Abi Al-Qutayri, Mahmoud Abdul Hadi, Sabina Al-Sarawi, Said F. Sci Rep Article In this paper, we present a novel Pt/CuO/Pt metal-oxide-metal (MOM) glucose sensor. The devices are fabricated using a simple, low-cost standard photolithography process. The unique planar structure of the device provides a large electrochemically active surface area, which acts as a nonenzymatic reservoir for glucose oxidation. The sensor has a linear sensing range between 2.2 mM and 10 mM of glucose concentration, which covers the blood glucose levels for an adult human. The distinguishing property of this sensor is its ability to measure glucose at neutral pH conditions (i.e. pH = 7). Furthermore, the dilution step commonly needed for CuO-based nonenzymatic electrochemical sensors to achieve an alkaline medium, which is essential to perform redox reactions in the absence of glucose oxidase, is eliminated, resulting in a lower-cost and more compact device. Nature Publishing Group UK 2019-04-02 /pmc/articles/PMC6445282/ /pubmed/30940837 http://dx.doi.org/10.1038/s41598-019-41892-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Abunahla, Heba Mohammad, Baker Alazzam, Anas Jaoude, Maguy Abi Al-Qutayri, Mahmoud Abdul Hadi, Sabina Al-Sarawi, Said F. MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title | MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title_full | MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title_fullStr | MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title_full_unstemmed | MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title_short | MOMSense: Metal-Oxide-Metal Elementary Glucose Sensor |
title_sort | momsense: metal-oxide-metal elementary glucose sensor |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445282/ https://www.ncbi.nlm.nih.gov/pubmed/30940837 http://dx.doi.org/10.1038/s41598-019-41892-w |
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