Cargando…

HIV-Exposed Uninfected Infants Have Increased Regulatory T Cells That Correlate With Decreased T Cell Function

Background: HIV-exposed uninfected infants (HEU) are at higher risk of severe infections, hospitalizations and death compared with HIV-unexposed uninfected infants (HUU), but the immune deficit underlying it is not known. To address this gap, we investigated T cell functionality and its relationship...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jalbert, Emilie, Williamson, Kayla M., Kroehl, Miranda E., Johnson, Michael J., Cutland, Clare, Madhi, Shabir A., Nunes, Marta C., Weinberg, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445326/ https://www.ncbi.nlm.nih.gov/pubmed/30972079 http://dx.doi.org/10.3389/fimmu.2019.00595

Ejemplares similares

Impaired functionality of antigen presenting cells in HIV- exposed uninfected infants in the first six months of life
por: Jalbert, Emilie, et al.
Publicado: (2022)

Neutralization and hemagglutination-inhibition antibodies following influenza vaccination of HIV-infected and HIV-uninfected pregnant women
por: Nunes, Marta C., et al.
Publicado: (2018)

Altered Natural Killer Cell Function in HIV-Exposed Uninfected Infants
por: Smith, Christiana, et al.
Publicado: (2017)

Bordetella pertussis Infection in South African HIV-Infected and HIV-Uninfected Mother–Infant Dyads: A Longitudinal Cohort Study
por: Nunes, Marta C., et al.
Publicado: (2016)

Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children
por: Nunes, Marta C., et al.
Publicado: (2014)

Evolution of the Gut Microbiome in HIV-Exposed Uninfected and Unexposed Infants during the First Year of Life
por: Jackson, Conner L., et al.
Publicado: (2022)

Burden of Respiratory Syncytial Virus Infection in South African Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Pregnant and Postpartum Women: A Longitudinal Cohort Study
por: Madhi, Shabir A, et al.
Publicado: (2018)

Bacterial and Respiratory Viral Interactions in the Etiology of Acute Otitis Media in HIV-infected and HIV-uninfected South African Children
por: Madhi, Shabir A., et al.
Publicado: (2015)

2572. Decreased T-Cell Response, but Appropriate Antibody Production to Tetanus Vaccine Among HIV-Exposed Uninfected Infants in Botswana
por: Smith, Christiana, et al.
Publicado: (2018)

Role of influenza vaccine during pregnancy in protecting against pertussis
por: Nunes, Marta C., et al.
Publicado: (2018)

Safety and Immunogenicity of Measles Vaccination in HIV-Infected and HIV-Exposed Uninfected Children: A Systematic Review and Meta-Analysis
por: Mutsaerts, Eleonora A.M.L., et al.
Publicado: (2018)

Cytomegalovirus infection in HIV-infected and uninfected individuals is characterized by circulating regulatory T cells of unconstrained antigenic specificity
por: Tovar-Salazar, Adriana, et al.
Publicado: (2017)

Immunogenicity and safety of a hexavalent pediatric vaccine in HIV-exposed infected and uninfected infants in Republic of South Africa
por: Koen, Anthonet, et al.
Publicado: (2020)

Streptococcus pneumoniae colonization in pneumococcal vaccine-naïve human immunodeficiency virus-exposed infected and -uninfected South African children
por: Nunes, Marta Coelho, et al.
Publicado: (2020)

Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV
por: Nunes, Marta C., et al.
Publicado: (2021)

Characterization of human respiratory syncytial virus (RSV) isolated from HIV‐exposed‐uninfected and HIV‐unexposed infants in South Africa during 2015‐2017
por: Liu, Hui, et al.
Publicado: (2020)

Influenza vaccination of pregnant women protects them over two consecutive influenza seasons in a randomized controlled trial
por: Mutsaerts, Eleonora, et al.
Publicado: (2016)

Immune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine
por: Weinberg, Adriana, et al.
Publicado: (2016)

T-cell responses to SARS-CoV-2 in unexposed South African women
por: Nunes, Marta C., et al.
Publicado: (2022)

Efficacy of Maternal Influenza Vaccination Against All-Cause Lower Respiratory Tract Infection Hospitalizations in Young Infants: Results From a Randomized Controlled Trial
por: Nunes, Marta C, et al.
Publicado: (2017)

Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV: a randomised controlled trial
por: Nunes, Marta C, et al.
Publicado: (2020)

The Immune System of HIV-Exposed Uninfected Infants
por: Abu-Raya, Bahaa, et al.
Publicado: (2016)

Unmasking the vulnerabilities of uninfected children exposed to HIV
por: Ramokolo, Vundli, et al.
Publicado: (2019)

Hemagglutinin Stalk Antibody Responses Following Trivalent Inactivated Influenza Vaccine Immunization of Pregnant Women and Association With Protection From Influenza Virus Illness
por: Dhar, Nisha, et al.
Publicado: (2020)

Strong HIV-1-Specific T Cell Responses in HIV-1-Exposed Uninfected Infants and Neonates Revealed after Regulatory T Cell Removal
por: Legrand, Fatema A., et al.
Publicado: (2006)

Increased Risk for Group B Streptococcus Sepsis in Young Infants Exposed to HIV, Soweto, South Africa, 2004–2008
por: Cutland, Clare L., et al.
Publicado: (2015)

Impaired T helper cell responses in human immunodeficiency virus‐exposed uninfected newborns
por: Brito‐Pérez, Yesenia, et al.
Publicado: (2021)

Outcome of HIV-exposed uninfected children undergoing surgery
por: Karpelowsky, Jonathan S, et al.
Publicado: (2011)

Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children
por: Kasule, Jingo, et al.
Publicado: (2018)

Analysis of the TCR Repertoire in HIV-Exposed but Uninfected Infants
por: Gabriel, Benjamin, et al.
Publicado: (2019)

Neurodevelopment of children who are HIV‐exposed and uninfected in Kenya
por: Bulterys, Michelle A., et al.
Publicado: (2023)

Surviving and Thriving—Shifting the Public Health Response to HIV-Exposed Uninfected Children: Report of the 3rd HIV-Exposed Uninfected Child Workshop
por: Slogrove, Amy L., et al.
Publicado: (2018)

Decreased diarrheal and respiratory disease in HIV exposed uninfected children following vaccination with rotavirus and pneumococcal conjugate vaccines
por: Ajibola, Gbolahan, et al.
Publicado: (2020)

Immunogenicity of influenza vaccines administered to pregnant women in randomized clinical trials in Mali and South Africa
por: Amin, Avnika B., et al.
Publicado: (2020)

B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine
por: Weinberg, Adriana, et al.
Publicado: (2018)

Age-specific associations with dental caries in HIV-infected, exposed but uninfected and HIV-unexposed uninfected children in Nigeria
por: Akhigbe, Paul, et al.
Publicado: (2022)

Contribution of Serologic Assays in the Evaluation of Influenza Virus Infection Rates and Vaccine Efficacy in Pregnant Women: Report From Randomized Controlled Trials
por: Madhi, Shabir A., et al.
Publicado: (2017)

Clinical Epidemiology of Bocavirus, Rhinovirus, Two Polyomaviruses and Four Coronaviruses in HIV-Infected and HIV-Uninfected South African Children
por: Nunes, Marta C., et al.
Publicado: (2014)

Pattern of Infectious Morbidity in HIV-Exposed Uninfected Infants and Children
por: Slogrove, Amy L., et al.
Publicado: (2016)

Mortality risk and associated factors in HIV‐exposed, uninfected children
por: Arikawa, Shino, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_aarltkq0ba20cad9ae0qbev44u