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Comparison of ion transport determinants between a TMEM16 chloride channel and phospholipid scramblase
Two TMEM16 family members, TMEM16A and TMEM16F, have different ion transport properties. Upon activation by intracellular Ca(2+), TMEM16A—a Ca(2+)-activated Cl(−) channel—is more selective for anions than cations, whereas TMEM16F—a phospholipid scramblase—appears to transport both cations and anions...
Autores principales: | Nguyen, Dung M., Chen, Louisa S., Yu, Wei-Ping, Chen, Tsung-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445582/ https://www.ncbi.nlm.nih.gov/pubmed/30670476 http://dx.doi.org/10.1085/jgp.201812270 |
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