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Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing
Kainate receptors are ligand-gated ion channels that have two major roles in the central nervous system: they mediate a postsynaptic component of excitatory neurotransmission at some glutamatergic synapses and modulate transmitter release at both excitatory and inhibitory synapses. Accumulating evid...
Autores principales: | Wilding, Timothy J., Huettner, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445585/ https://www.ncbi.nlm.nih.gov/pubmed/30498132 http://dx.doi.org/10.1085/jgp.201812234 |
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