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Ano1 mediates pressure-sensitive contraction frequency changes in mouse lymphatic collecting vessels
Lymphatic collecting vessels exhibit spontaneous contractions with a pressure-dependent contraction frequency. The initiation of contraction has been proposed to be mediated by the activity of a Ca(2+)-activated Cl(−) channel (CaCC). Here, we show that the canonical CaCC Anoctamin 1 (Ano1, TMEM16a)...
Autores principales: | Zawieja, Scott D., Castorena, Jorge A., Gui, Peichun, Li, Min, Bulley, Simon A., Jaggar, Jonathan H., Rock, Jason R., Davis, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445586/ https://www.ncbi.nlm.nih.gov/pubmed/30862712 http://dx.doi.org/10.1085/jgp.201812294 |
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