Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture

Arthritis is thought to cause oxidative stress in synovial fluid in humans, but there have been few reports in horses. To evaluate oxidative stress in synovial fluid in horses, this study used 19 horses with unilateral fracture of the carpal joint bone. Synovial fluid was collected from the carpal j...

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Autores principales: TSUZUKI, Nao, KANBAYASHI, Yoshinori, KUSANO, Kanichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Equine Science 2019
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445753/
https://www.ncbi.nlm.nih.gov/pubmed/30944542
http://dx.doi.org/10.1294/jes.30.13
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author TSUZUKI, Nao
KANBAYASHI, Yoshinori
KUSANO, Kanichi
author_facet TSUZUKI, Nao
KANBAYASHI, Yoshinori
KUSANO, Kanichi
author_sort TSUZUKI, Nao
collection PubMed
description Arthritis is thought to cause oxidative stress in synovial fluid in humans, but there have been few reports in horses. To evaluate oxidative stress in synovial fluid in horses, this study used 19 horses with unilateral fracture of the carpal joint bone. Synovial fluid was collected from the carpal joint on the fracture (arthritis group) and contralateral (control group) sides. Diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) were then measured, and the oxidative stress index (OSI) was calculated. d-ROMs and OSI of the arthritis group were significantly higher than the control group. BAP of the arthritis group was significantly lower than the control group. Thus, this study revealed that oxidative stress develops in the synovial fluid of horses during arthritis.
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spelling pubmed-64457532019-04-03 Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture TSUZUKI, Nao KANBAYASHI, Yoshinori KUSANO, Kanichi J Equine Sci Note Arthritis is thought to cause oxidative stress in synovial fluid in humans, but there have been few reports in horses. To evaluate oxidative stress in synovial fluid in horses, this study used 19 horses with unilateral fracture of the carpal joint bone. Synovial fluid was collected from the carpal joint on the fracture (arthritis group) and contralateral (control group) sides. Diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) were then measured, and the oxidative stress index (OSI) was calculated. d-ROMs and OSI of the arthritis group were significantly higher than the control group. BAP of the arthritis group was significantly lower than the control group. Thus, this study revealed that oxidative stress develops in the synovial fluid of horses during arthritis. The Japanese Society of Equine Science 2019-04-03 2019-03 /pmc/articles/PMC6445753/ /pubmed/30944542 http://dx.doi.org/10.1294/jes.30.13 Text en ©2019 The Japanese Society of Equine Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Note
TSUZUKI, Nao
KANBAYASHI, Yoshinori
KUSANO, Kanichi
Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title_full Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title_fullStr Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title_full_unstemmed Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title_short Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture
title_sort markers for oxidative stress in the synovial fluid of thoroughbred horses with carpal bone fracture
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445753/
https://www.ncbi.nlm.nih.gov/pubmed/30944542
http://dx.doi.org/10.1294/jes.30.13
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