SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior

Antidepressants that block the serotonin transporter, (Slc6a4/SERT), selective serotonin reuptake inhibitors (SSRIs) improve mood in adults but have paradoxical long-term effects when administered during perinatal periods, increasing the risk to develop anxiety and depression. The basis for this dev...

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Detalles Bibliográficos
Autores principales: Soiza-Reilly, M., Meye, F. J., Olusakin, J., Telley, L., Petit, E., Chen, X., Mameli, M., Jabaudon, D., Sze, J.-Y., Gaspar, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445781/
https://www.ncbi.nlm.nih.gov/pubmed/30279456
http://dx.doi.org/10.1038/s41380-018-0260-9

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