TiO(2) Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry

In drug discovery, it is important to identify phase I metabolic modifications as early as possible to screen for inactivation of drugs and/or activation of prodrugs. As the major class of reactions in phase I metabolism is oxidation reactions, oxidation of drugs with TiO(2) photocatalysis can be us...

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Detalles Bibliográficos
Autores principales: van Geenen, Fred A. M. G., Franssen, Maurice C. R., Miikkulainen, Ville, Ritala, Mikko, Zuilhof, Han, Kostiainen, Risto, Nielen, Michel W. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445813/
https://www.ncbi.nlm.nih.gov/pubmed/30617860
http://dx.doi.org/10.1007/s13361-018-2120-x

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