Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model

Cryptococcus neoformans is an encapsulated fungal pathogen that causes meningoencephalitis. There are no prophylactic tools for cryptococcosis. Previously, our group showed that a C. neoformans mutant lacking the gene encoding sterylglucosidase (Δsgl1) induced protection in both immunocompetent and...

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Detalles Bibliográficos
Autores principales: Colombo, Ana Caroline, Rella, Antonella, Normile, Tyler, Joffe, Luna S., Tavares, Patricia M., de S. Araújo, Glauber R., Frases, Susana, Orner, Erika P., Farnoud, Amir M., Fries, Bettina C., Sheridan, Brian, Nimrichter, Leonardo, Rodrigues, Marcio L., Del Poeta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445945/
https://www.ncbi.nlm.nih.gov/pubmed/30940711
http://dx.doi.org/10.1128/mBio.02909-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445945/
https://www.ncbi.nlm.nih.gov/pubmed/30940711
http://dx.doi.org/10.1128/mBio.02909-18

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