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Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model
Cryptococcus neoformans is an encapsulated fungal pathogen that causes meningoencephalitis. There are no prophylactic tools for cryptococcosis. Previously, our group showed that a C. neoformans mutant lacking the gene encoding sterylglucosidase (Δsgl1) induced protection in both immunocompetent and...
Autores principales: | Colombo, Ana Caroline, Rella, Antonella, Normile, Tyler, Joffe, Luna S., Tavares, Patricia M., de S. Araújo, Glauber R., Frases, Susana, Orner, Erika P., Farnoud, Amir M., Fries, Bettina C., Sheridan, Brian, Nimrichter, Leonardo, Rodrigues, Marcio L., Del Poeta, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445945/ https://www.ncbi.nlm.nih.gov/pubmed/30940711 http://dx.doi.org/10.1128/mBio.02909-18 |
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