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Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

During blood-stage malaria, the innate immune system initiates the production of pro-inflammatory cytokines, including IFN-γ, that are critical to host defense and responsible for severe disease. Nonetheless, the innate immune pathways activated during this process in human malaria remain poorly und...

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Detalles Bibliográficos
Autores principales:	Coch, Christoph, Hommertgen, Benjamin, Zillinger, Thomas, Daßler-Plenker, Juliane, Putschli, Bastian, Nastaly, Maximilian, Kümmerer, Beate M., Scheunemann, Johanna F., Schumak, Beatrix, Specht, Sabine, Schlee, Martin, Barchet, Winfried, Hoerauf, Achim, Bartok, Eva, Hartmann, Gunther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445952/ https://www.ncbi.nlm.nih.gov/pubmed/30972055 http://dx.doi.org/10.3389/fimmu.2019.00371

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