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Re-thinking Alzheimer's disease therapeutic targets using gene-based tests

BACKGROUND: Alzheimer's disease (AD) is a devastating condition with no known effective drug treatments. Existing drugs only alleviate symptoms. Given repeated expensive drug failures, we assessed systematically whether approved and investigational AD drugs are targeting products of genes stron...

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Detalles Bibliográficos
Autores principales: Kwok, Man Ki, Lin, Shi Lin, Schooling, C. Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446018/
https://www.ncbi.nlm.nih.gov/pubmed/30314892
http://dx.doi.org/10.1016/j.ebiom.2018.10.001