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Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker

Mycobacterium chimaera, a nontuberculous mycobacterium, is a member of the Mycobacterium avium complex (MAC). This microorganism has recently gained significant notoriety for its association with outbreaks in patients exposed to contaminated heater –cooler devices used during open heart surgeries. W...

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Detalles Bibliográficos
Autores principales: Rosero, Christian I., Shams, Wael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446050/
https://www.ncbi.nlm.nih.gov/pubmed/30989052
http://dx.doi.org/10.1016/j.idcr.2019.e00526
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author Rosero, Christian I.
Shams, Wael E.
author_facet Rosero, Christian I.
Shams, Wael E.
author_sort Rosero, Christian I.
collection PubMed
description Mycobacterium chimaera, a nontuberculous mycobacterium, is a member of the Mycobacterium avium complex (MAC). This microorganism has recently gained significant notoriety for its association with outbreaks in patients exposed to contaminated heater –cooler devices used during open heart surgeries. We report a case of Mycobacterium chimaera pulmonary infection in a healthcare worker who presented with cough, low grade fever and weight loss with evidence of a lung mass that was initially thought to be a tumor on CT scan imaging. The patient underwent partial left lung lobectomy and pathology revealed necrotizing granulomas with acid fast bacilli and a culture grew M. chimaera. The patient received combination antimycobacterial therapy according to susceptibility results for twelve months with complete resolution of his symptoms and radiographic findings. Infection Control investigation could not find a source of infection in the hospital where he worked during the last ten years. However, the patient rotated in different hospitals before coming to work at this facility and assisted in surgeries in several operating rooms where the heater-cooler devices in question were used.
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spelling pubmed-64460502019-04-15 Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker Rosero, Christian I. Shams, Wael E. IDCases Article Mycobacterium chimaera, a nontuberculous mycobacterium, is a member of the Mycobacterium avium complex (MAC). This microorganism has recently gained significant notoriety for its association with outbreaks in patients exposed to contaminated heater –cooler devices used during open heart surgeries. We report a case of Mycobacterium chimaera pulmonary infection in a healthcare worker who presented with cough, low grade fever and weight loss with evidence of a lung mass that was initially thought to be a tumor on CT scan imaging. The patient underwent partial left lung lobectomy and pathology revealed necrotizing granulomas with acid fast bacilli and a culture grew M. chimaera. The patient received combination antimycobacterial therapy according to susceptibility results for twelve months with complete resolution of his symptoms and radiographic findings. Infection Control investigation could not find a source of infection in the hospital where he worked during the last ten years. However, the patient rotated in different hospitals before coming to work at this facility and assisted in surgeries in several operating rooms where the heater-cooler devices in question were used. Elsevier 2019-03-26 /pmc/articles/PMC6446050/ /pubmed/30989052 http://dx.doi.org/10.1016/j.idcr.2019.e00526 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Rosero, Christian I.
Shams, Wael E.
Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title_full Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title_fullStr Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title_full_unstemmed Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title_short Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
title_sort mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446050/
https://www.ncbi.nlm.nih.gov/pubmed/30989052
http://dx.doi.org/10.1016/j.idcr.2019.e00526
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