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Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse

There are multiple causes of dyspnea upon exertion in young, healthy patients to primarily include asthma and exercise-induced bronchospasm. Excessive dynamic airway collapse (EDAC) describes focal collapse of the trachea or main bronchi with maintained structural integrity of the cartilaginous ring...

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Detalles Bibliográficos
Autores principales: Rendo, Matthew, Sjulin, Tyson J., Morris, Michael J., Burguete, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446124/
https://www.ncbi.nlm.nih.gov/pubmed/30989047
http://dx.doi.org/10.1016/j.rmcr.2019.100827
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author Rendo, Matthew
Sjulin, Tyson J.
Morris, Michael J.
Burguete, Sergio
author_facet Rendo, Matthew
Sjulin, Tyson J.
Morris, Michael J.
Burguete, Sergio
author_sort Rendo, Matthew
collection PubMed
description There are multiple causes of dyspnea upon exertion in young, healthy patients to primarily include asthma and exercise-induced bronchospasm. Excessive dynamic airway collapse (EDAC) describes focal collapse of the trachea or main bronchi with maintained structural integrity of the cartilaginous rings. It is commonly associated with pulmonary disorders like bronchiectasis, chronic obstructive pulmonary disease and asthma. It is believed to result secondary to airway obstruction in these conditions. While uncommon in young, healthy adults, it has recently been found as a cause of dyspnea in this population. Inducible laryngeal obstruction (ILO) is an umbrella term that describes an induced, intermittent upper airway impediment. While ILO is found in 10% of young patients with exertional dyspnea, it is primarily inspiratory in nature due to paradoxical closure of the glottis or supraglottis. This report highlights the presentation of a United States Army soldier who after a deployment was given a diagnosis of asthma, later found to have ILO and was subsequently diagnosed with concurrent EDAC. We follow up with a literature review and discussion of symptomatology, diagnosis, exercise bronchoscopy, and treatment modalities for both EDAC and ILO.
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spelling pubmed-64461242019-04-15 Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse Rendo, Matthew Sjulin, Tyson J. Morris, Michael J. Burguete, Sergio Respir Med Case Rep Article There are multiple causes of dyspnea upon exertion in young, healthy patients to primarily include asthma and exercise-induced bronchospasm. Excessive dynamic airway collapse (EDAC) describes focal collapse of the trachea or main bronchi with maintained structural integrity of the cartilaginous rings. It is commonly associated with pulmonary disorders like bronchiectasis, chronic obstructive pulmonary disease and asthma. It is believed to result secondary to airway obstruction in these conditions. While uncommon in young, healthy adults, it has recently been found as a cause of dyspnea in this population. Inducible laryngeal obstruction (ILO) is an umbrella term that describes an induced, intermittent upper airway impediment. While ILO is found in 10% of young patients with exertional dyspnea, it is primarily inspiratory in nature due to paradoxical closure of the glottis or supraglottis. This report highlights the presentation of a United States Army soldier who after a deployment was given a diagnosis of asthma, later found to have ILO and was subsequently diagnosed with concurrent EDAC. We follow up with a literature review and discussion of symptomatology, diagnosis, exercise bronchoscopy, and treatment modalities for both EDAC and ILO. Elsevier 2019-03-28 /pmc/articles/PMC6446124/ /pubmed/30989047 http://dx.doi.org/10.1016/j.rmcr.2019.100827 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Rendo, Matthew
Sjulin, Tyson J.
Morris, Michael J.
Burguete, Sergio
Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title_full Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title_fullStr Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title_full_unstemmed Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title_short Upper airway wheezing: Inducible laryngeal obstruction vs. excessive dynamic airway collapse
title_sort upper airway wheezing: inducible laryngeal obstruction vs. excessive dynamic airway collapse
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446124/
https://www.ncbi.nlm.nih.gov/pubmed/30989047
http://dx.doi.org/10.1016/j.rmcr.2019.100827
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