Cargando…

Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model

Uncontrolled activation of transforming growth factor beta (TGF-β) family members is hypothesized to participate in type 2 diabetes (T2D) dependent diabetic nephropathy (DN). We evaluated and compared downstream activation of the Smad2-signaling pathway in kidney samples from T2D patients to kidneys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomsen, Lise Høj, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, García de Vinuesa, Amaya, Hansen, Troels Krarup, de Heer, Emile, ten Dijke, Peter, Rosendahl, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446227/ https://www.ncbi.nlm.nih.gov/pubmed/28805484 http://dx.doi.org/10.1080/0886022X.2017.1361837

Ejemplares similares

Deletion of Smad3 protects against diabetic myocardiopathy in db/db mice
por: Dong, Li, et al.
Publicado: (2021)

Smad3 Mediates Diabetic Dyslipidemia and Fatty Liver in db/db Mice by Targeting PPARδ
por: He, Huijun, et al.
Publicado: (2023)

Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice
por: Yang, Bo, et al.
Publicado: (2019)

Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice
por: Sembach, Frederikke E., et al.
Publicado: (2019)

Dendrobium Mixture Ameliorates Diabetic Nephropathy in db/db Mice by Regulating the TGF-β1/Smads Signaling Pathway
por: Chen, Yong, et al.
Publicado: (2021)

AANG Prevents Smad3-dependent Diabetic Nephropathy by Restoring Pancreatic β-Cell Development in db/db Mice
por: Chung, Jeff Yat-Fai, et al.
Publicado: (2022)

Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db/Db Mice
por: Zhang, Xiang, et al.
Publicado: (2020)

Anti-diabetic activities of catalpol in db/db mice
por: Bao, Qinwen, et al.
Publicado: (2016)

Renoprotective Effect of Formononetin by Suppressing Smad3 Expression in Db/Db Mice
por: Lv, Jiawei, et al.
Publicado: (2020)

Segmentation of the Pathophysiological Stages of Diabetic Changes in the db/db Mouse
por: Yamazaki, Masaki, et al.
Publicado: (2009)

Effect of Ezetimibe on Insulin Secretion in db/db Diabetic Mice
por: Zhong, Yong, et al.
Publicado: (2012)

Mycophenolate Mofetil Ameliorates Diabetic Nephropathy in db/db Mice
por: Seo, Jung-Woo, et al.
Publicado: (2015)

Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes
por: Yang, Qin, et al.
Publicado: (2015)

Diabetes Alters Diurnal Rhythm of Electroretinogram in db/db Mice
por: Di, Rong, et al.
Publicado: (2019)

Zinc Prevents the Development of Diabetic Cardiomyopathy in db/db Mice
por: Wang, Shudong, et al.
Publicado: (2017)

Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy
por: Tang, Fengjuan, et al.
Publicado: (2017)

Protective Effects of Astragaloside IV on db/db Mice with Diabetic Retinopathy
por: Ding, Yuzhi, et al.
Publicado: (2014)

Linagliptin alleviates fatty liver disease in diabetic db/db mice
por: Michurina, Svetlana V, et al.
Publicado: (2016)

Carvacrol may alleviate vascular inflammation in diabetic db/db mice
por: Zhao, Wei, et al.
Publicado: (2020)

MG53 Does Not Manifest the Development of Diabetes in db/db Mice
por: Wang, Qiang, et al.
Publicado: (2020)

The PKD Inhibitor CID755673 Enhances Cardiac Function in Diabetic db/db Mice
por: Venardos, Kylie, et al.
Publicado: (2015)

Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy
por: Liu, Mengyang, et al.
Publicado: (2015)

Effects of insulin and the glucagon‐like peptide 1 receptor agonist liraglutide on the kidney proteome in db/db mice
por: Liljedahl, Leena, et al.
Publicado: (2017)

Huangqi decoction ameliorates kidney injury in db/db mice by regulating the BMP/Smad signaling pathway
por: Chen, Ying, et al.
Publicado: (2023)

Proteases in Plasma and Kidney of db/db Mice as Markers of Diabetes-Induced Nephropathy
por: Hadler-Olsen, E., et al.
Publicado: (2011)

The db/db Mouse: A Useful Model for the Study of Diabetic Retinal Neurodegeneration
por: Bogdanov, Patricia, et al.
Publicado: (2014)

Shengmai San Ameliorates Myocardial Dysfunction and Fibrosis in Diabetic db/db Mice
por: Zhao, Juan, et al.
Publicado: (2016)

NaoXinTong Inhibits the Development of Diabetic Retinopathy in db/db Mice
por: Liu, Mengyang, et al.
Publicado: (2015)

Transcriptional Profile of Kidney from Type 2 Diabetic db/db Mice
por: Zhang, Haojun, et al.
Publicado: (2017)

Metformin accelerates wound healing in type 2 diabetic db/db mice
por: Han, Xue, et al.
Publicado: (2017)

Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice
por: Li, Meng, et al.
Publicado: (2019)

Effect of hyperglycemia and rosiglitazone on renal and urinary neprilysin in db/db diabetic mice
por: Alawi, Laale F., et al.
Publicado: (2020)

Valsartan alleviates the blood–brain barrier dysfunction in db/db diabetic mice
por: Cai, Longxue, et al.
Publicado: (2021)

Galantamine improves glycemic control and diabetic nephropathy in Lepr(db/db) mice
por: Meng, Qinghe, et al.
Publicado: (2023)

[Corrigendum] Carvacrol may alleviate vascular inflammation in diabetic db/db mice
por: Zhao, Wei, et al.
Publicado: (2023)

Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse: A Model of Type 2 Diabetes
por: Pande, Manjusha, et al.
Publicado: (2011)

Clopidogrel delays and can reverse diabetic nephropathy pathogenesis in type 2 diabetic db/db mice
por: Li, Hong-Qin, et al.
Publicado: (2022)

C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway
por: You, Yong-Ke, et al.
Publicado: (2016)

Portulaca oleracea Ameliorates Diabetic Vascular Inflammation and Endothelial Dysfunction in db/db Mice
por: Lee, An Sook, et al.
Publicado: (2012)

Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice
por: Liu, Hsien Yueh, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qgstu9a7rg62jtvsd6ahen3j65