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Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis

INTRODUCTION: Abnormal glycolytic metabolism contributes to joint inflammation and destruction in rheumatoid arthritis (RA). We examine the expression and function of hexokinases in RA and evaluate the potential of their specific inhibitor for clinical treatment. METHODS: Detection of HKs was assess...

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Detalles Bibliográficos
Autores principales: Song, Guanhua, Lu, Qiqi, Fan, Hua, Zhang, Xiumei, Ge, Luna, Tian, Ruisong, Wang, Shiguan, Feng, Tingting, Pan, Jihong, Feng, Jingjing, Xiao, Yabo, Yi, Xin, Ren, Ningxin, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446273/
https://www.ncbi.nlm.nih.gov/pubmed/30944034
http://dx.doi.org/10.1186/s13075-019-1865-3