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Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

OBJECTIVE: Therapeutic effects of focal adhesion kinase (FAK) inhibition using a small molecule inhibitor was evaluated in apolipoprotein E (apoE) knockout (KO) and low-density lipoprotein receptor (LDLr) KO mouse atherosclerosis models. RESULTS: The prevention trial consisted of an 8-week treatment...

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Detalles Bibliográficos
Autores principales:	Yamaura, Takeshi, Kasaoka, Tatsuhiko, Iijima, Naoko, Kimura, Masaaki, Hatakeyama, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446301/ https://www.ncbi.nlm.nih.gov/pubmed/30940182 http://dx.doi.org/10.1186/s13104-019-4220-5

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