Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

BACKGROUND: Notch intercellular communication instructs tissue-specific T-cell development and function. In this study, we explored the roles of dendritic cell (DC)-expressed Notch ligands in the regulation of T-cell effector function. METHODS: We generated mice with CD11c lineage-specific deletion...

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Detalles Bibliográficos
Autores principales: Tchekneva, Elena E., Goruganthu, Mounika U.L., Uzhachenko, Roman V., Thomas, Portia L., Antonucci, Anneliese, Chekneva, Irina, Koenig, Michael, Piao, Longzhu, Akhter, Anwari, de Aquino, Maria Teresa P., Ranganathan, Parvathi, Long, Nicholas, Magliery, Thomas, Valujskikh, Anna, Evans, Jason V., Arasada, Rajeswara R., Massion, Pierre P., Carbone, David P., Shanker, Anil, Dikov, Mikhail M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446314/
https://www.ncbi.nlm.nih.gov/pubmed/30940183
http://dx.doi.org/10.1186/s40425-019-0566-4

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