RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

BACKGROUND: Multiple gene expression studies have been performed separately in peripheral blood, lung, and airway tissues to study COPD. We performed RNA-sequencing gene expression profiling of large-airway epithelium, alveolar macrophage and peripheral blood samples from the same subset of COPD cas...

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Detalles Bibliográficos
Autores principales: Morrow, Jarrett D., Chase, Robert P., Parker, Margaret M., Glass, Kimberly, Seo, Minseok, Divo, Miguel, Owen, Caroline A., Castaldi, Peter, DeMeo, Dawn L., Silverman, Edwin K., Hersh, Craig P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446359/
https://www.ncbi.nlm.nih.gov/pubmed/30940135
http://dx.doi.org/10.1186/s12931-019-1032-z

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