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Generation and maintenance of acentric stable double minutes from chromosome arms in inter-species hybrid cells

BACKGROUND: Extrachromosomal acentric double minutes (DMs) contribute to human malignancy by carrying amplified oncogenes. Recent cancer genomics revealed that the pulverization of defined chromosome arms (chromothripsis) may generate DMs, however, nobody had actually generated DMs from chromosome a...

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Detalles Bibliográficos
Autores principales:	Shimizu, Noriaki, Kapoor, Rita, Naniwa, Shuhei, Sakamaru, Naoto, Yamada, Taku, Yamamura, You-ki, Utani, Koh-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446505/ https://www.ncbi.nlm.nih.gov/pubmed/31041889 http://dx.doi.org/10.1186/s12860-019-0186-3

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