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The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise
Nucleosomal organization at gene promoters is critical for transcription, with a nucleosome-depleted region (NDR) at transcription start sites (TSSs) being required for transcription initiation. How NDRs and the precise positioning of the +1 nucleosomes are maintained on active genes remains unclear...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446542/ https://www.ncbi.nlm.nih.gov/pubmed/30819819 http://dx.doi.org/10.1101/gad.321489.118 |