The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise

Nucleosomal organization at gene promoters is critical for transcription, with a nucleosome-depleted region (NDR) at transcription start sites (TSSs) being required for transcription initiation. How NDRs and the precise positioning of the +1 nucleosomes are maintained on active genes remains unclear...

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Detalles Bibliográficos
Autores principales: Lam, Kin Chung, Chung, Ho-Ryun, Semplicio, Giuseppe, Iyer, Shantanu S., Gaub, Aline, Bhardwaj, Vivek, Holz, Herbert, Georgiev, Plamen, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446542/
https://www.ncbi.nlm.nih.gov/pubmed/30819819
http://dx.doi.org/10.1101/gad.321489.118

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