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TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth

Tgif1 (thymine–guanine-interacting factor 1) and Tgif2 repress gene expression by binding directly to DNA or interacting with transforming growth factor (TGF) β-responsive SMADs. Tgifs are essential for embryogenesis and may function in tumor progression. By analyzing both gain and loss of Tgif func...

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Detalles Bibliográficos
Autores principales:	Shah, Anant, Melhuish, Tiffany A., Fox, Todd E., Frierson, Henry F., Wotton, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446543/ https://www.ncbi.nlm.nih.gov/pubmed/30808659 http://dx.doi.org/10.1101/gad.320127.118

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