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Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446611/ http://dx.doi.org/10.1002/advs.201970043 |
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author | Liu, Jia Chang, Bingcheng Li, Qilin Xu, Luming Liu, Xingxin Wang, Guobin Wang, Zheng Wang, Lin |
author_facet | Liu, Jia Chang, Bingcheng Li, Qilin Xu, Luming Liu, Xingxin Wang, Guobin Wang, Zheng Wang, Lin |
author_sort | Liu, Jia |
collection | PubMed |
description | Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsive, celecoxib‐modified nanosystem that efficiently enhances doxorubicin‐based chemotherapy and suppresses cancer repopulation by abrogating doxorubicin‐induced enhancement of cancer stemness, metastasis and drug resistance. [Image: see text] |
format | Online Article Text |
id | pubmed-6446611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64466112019-04-15 Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) Liu, Jia Chang, Bingcheng Li, Qilin Xu, Luming Liu, Xingxin Wang, Guobin Wang, Zheng Wang, Lin Adv Sci (Weinh) Inside Back Cover Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsive, celecoxib‐modified nanosystem that efficiently enhances doxorubicin‐based chemotherapy and suppresses cancer repopulation by abrogating doxorubicin‐induced enhancement of cancer stemness, metastasis and drug resistance. [Image: see text] John Wiley and Sons Inc. 2019-04-03 /pmc/articles/PMC6446611/ http://dx.doi.org/10.1002/advs.201970043 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Back Cover Liu, Jia Chang, Bingcheng Li, Qilin Xu, Luming Liu, Xingxin Wang, Guobin Wang, Zheng Wang, Lin Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title | Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title_full | Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title_fullStr | Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title_full_unstemmed | Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title_short | Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) |
title_sort | cancer chemotherapy: redox‐responsive dual drug delivery nanosystem suppresses cancer repopulation by abrogating doxorubicin‐promoted cancer stemness, metastasis, and drug resistance (adv. sci. 7/2019) |
topic | Inside Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446611/ http://dx.doi.org/10.1002/advs.201970043 |
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