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Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)

Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsi...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Chang, Bingcheng, Li, Qilin, Xu, Luming, Liu, Xingxin, Wang, Guobin, Wang, Zheng, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446611/
http://dx.doi.org/10.1002/advs.201970043
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author Liu, Jia
Chang, Bingcheng
Li, Qilin
Xu, Luming
Liu, Xingxin
Wang, Guobin
Wang, Zheng
Wang, Lin
author_facet Liu, Jia
Chang, Bingcheng
Li, Qilin
Xu, Luming
Liu, Xingxin
Wang, Guobin
Wang, Zheng
Wang, Lin
author_sort Liu, Jia
collection PubMed
description Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsive, celecoxib‐modified nanosystem that efficiently enhances doxorubicin‐based chemotherapy and suppresses cancer repopulation by abrogating doxorubicin‐induced enhancement of cancer stemness, metastasis and drug resistance. [Image: see text]
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spelling pubmed-64466112019-04-15 Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019) Liu, Jia Chang, Bingcheng Li, Qilin Xu, Luming Liu, Xingxin Wang, Guobin Wang, Zheng Wang, Lin Adv Sci (Weinh) Inside Back Cover Chemotherapy effectiveness is greatly challenged by chemodrugs' intrinsic pathological interactions with tumor cells, which enhance cancer stemness, invasiveness and acquired drug resistance. In article number 1801987, Guobin Wang, Zheng Wang, Lin Wang, and co‐workers construct a redox‐responsive, celecoxib‐modified nanosystem that efficiently enhances doxorubicin‐based chemotherapy and suppresses cancer repopulation by abrogating doxorubicin‐induced enhancement of cancer stemness, metastasis and drug resistance. [Image: see text] John Wiley and Sons Inc. 2019-04-03 /pmc/articles/PMC6446611/ http://dx.doi.org/10.1002/advs.201970043 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Back Cover
Liu, Jia
Chang, Bingcheng
Li, Qilin
Xu, Luming
Liu, Xingxin
Wang, Guobin
Wang, Zheng
Wang, Lin
Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title_full Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title_fullStr Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title_full_unstemmed Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title_short Cancer Chemotherapy: Redox‐Responsive Dual Drug Delivery Nanosystem Suppresses Cancer Repopulation by Abrogating Doxorubicin‐Promoted Cancer Stemness, Metastasis, and Drug Resistance (Adv. Sci. 7/2019)
title_sort cancer chemotherapy: redox‐responsive dual drug delivery nanosystem suppresses cancer repopulation by abrogating doxorubicin‐promoted cancer stemness, metastasis, and drug resistance (adv. sci. 7/2019)
topic Inside Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446611/
http://dx.doi.org/10.1002/advs.201970043
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