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Long-term outcomes of cataract surgery in children with uveitis

PURPOSE: To evaluate the long-term outcomes of cataract surgery in children with uveitis. METHODS: Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center...

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Autores principales: Yangzes, Sonam, Seth, Natasha Gautam, Singh, Ramandeep, Gupta, Parul Chawla, Jinagal, Jitender, Pandav, Surinder Singh, Gupta, Vishali, Gupta, Amod, Ram, Jagat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446648/
https://www.ncbi.nlm.nih.gov/pubmed/30900580
http://dx.doi.org/10.4103/ijo.IJO_846_18
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author Yangzes, Sonam
Seth, Natasha Gautam
Singh, Ramandeep
Gupta, Parul Chawla
Jinagal, Jitender
Pandav, Surinder Singh
Gupta, Vishali
Gupta, Amod
Ram, Jagat
author_facet Yangzes, Sonam
Seth, Natasha Gautam
Singh, Ramandeep
Gupta, Parul Chawla
Jinagal, Jitender
Pandav, Surinder Singh
Gupta, Vishali
Gupta, Amod
Ram, Jagat
author_sort Yangzes, Sonam
collection PubMed
description PURPOSE: To evaluate the long-term outcomes of cataract surgery in children with uveitis. METHODS: Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main outcome measures were visual acuity and postoperative complications. RESULTS: We recruited 37 children (58 eyes) who were diagnosed with uveitic cataract and underwent cataract surgery. The etiology of uveitis included juvenile idiopathic arthritis (n = 19), presumed intraocular tuberculosis (n = 8), idiopathic (n = 4), Behçet's disease (n = 2), Vogt–Koyanagi–Harada syndrome (n = 2), human leukocyte antigen B-27 associated uveitis (n = 1), and toxocariasis (n = 1). Phacoemulsification with intraocular lens (IOL) implantation was performed in 17 patients (27 eyes; 46.55%), while 20 patients (31 eyes; 53.44%) were left aphakic after pars plan lensectomy and vitrectomy. At an average follow-up of 3.69 ± 7.2 (SD) years, all cases had significant improvement in corrected distance visual acuity post cataract extraction; visual acuity of 20/40 or more was achieved in 32 eyes (55.17%). The most common complication was capsular opacification (37.93%). Incidence of secondary procedures as well as glaucoma was not statistically different in patients undergoing IOL implantation from those who were aphakic. CONCLUSION: Even though number of secondary procedures was more in pseudophakic group, meticulous choice of surgical technique and adequate immunosuppression lead to a modest gain of visual acuity in children undergoing IOL implantation in uveitis. However, scrupulous case selection and aggressive control of pre- and postoperative intraocular inflammation are the key factors in the postoperative success of these patients.
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spelling pubmed-64466482019-04-23 Long-term outcomes of cataract surgery in children with uveitis Yangzes, Sonam Seth, Natasha Gautam Singh, Ramandeep Gupta, Parul Chawla Jinagal, Jitender Pandav, Surinder Singh Gupta, Vishali Gupta, Amod Ram, Jagat Indian J Ophthalmol Original Article PURPOSE: To evaluate the long-term outcomes of cataract surgery in children with uveitis. METHODS: Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main outcome measures were visual acuity and postoperative complications. RESULTS: We recruited 37 children (58 eyes) who were diagnosed with uveitic cataract and underwent cataract surgery. The etiology of uveitis included juvenile idiopathic arthritis (n = 19), presumed intraocular tuberculosis (n = 8), idiopathic (n = 4), Behçet's disease (n = 2), Vogt–Koyanagi–Harada syndrome (n = 2), human leukocyte antigen B-27 associated uveitis (n = 1), and toxocariasis (n = 1). Phacoemulsification with intraocular lens (IOL) implantation was performed in 17 patients (27 eyes; 46.55%), while 20 patients (31 eyes; 53.44%) were left aphakic after pars plan lensectomy and vitrectomy. At an average follow-up of 3.69 ± 7.2 (SD) years, all cases had significant improvement in corrected distance visual acuity post cataract extraction; visual acuity of 20/40 or more was achieved in 32 eyes (55.17%). The most common complication was capsular opacification (37.93%). Incidence of secondary procedures as well as glaucoma was not statistically different in patients undergoing IOL implantation from those who were aphakic. CONCLUSION: Even though number of secondary procedures was more in pseudophakic group, meticulous choice of surgical technique and adequate immunosuppression lead to a modest gain of visual acuity in children undergoing IOL implantation in uveitis. However, scrupulous case selection and aggressive control of pre- and postoperative intraocular inflammation are the key factors in the postoperative success of these patients. Wolters Kluwer - Medknow 2019-04 /pmc/articles/PMC6446648/ /pubmed/30900580 http://dx.doi.org/10.4103/ijo.IJO_846_18 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Yangzes, Sonam
Seth, Natasha Gautam
Singh, Ramandeep
Gupta, Parul Chawla
Jinagal, Jitender
Pandav, Surinder Singh
Gupta, Vishali
Gupta, Amod
Ram, Jagat
Long-term outcomes of cataract surgery in children with uveitis
title Long-term outcomes of cataract surgery in children with uveitis
title_full Long-term outcomes of cataract surgery in children with uveitis
title_fullStr Long-term outcomes of cataract surgery in children with uveitis
title_full_unstemmed Long-term outcomes of cataract surgery in children with uveitis
title_short Long-term outcomes of cataract surgery in children with uveitis
title_sort long-term outcomes of cataract surgery in children with uveitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446648/
https://www.ncbi.nlm.nih.gov/pubmed/30900580
http://dx.doi.org/10.4103/ijo.IJO_846_18
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