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Arsenic Trioxide Inhibits the Metastasis of Small Cell Lung Cancer by Blocking Calcineurin-Nuclear Factor of Activated T Cells (NFAT) Signaling
BACKGROUND: The inhibitory effect of arsenic trioxide (As(2)O(3)) on lung cancer has been reported in some preclinical studies. However, its effect on small cell lung cancer (SCLC) has been poorly explored. Calcineurin and its substrate, nuclear factor of activated T cells (NFAT), mediate the downst...
Autores principales: | Zheng, Jin-Cheng, Chang, Ke-Jie, Jin, Yu-Xiang, Zhao, Xue-Wei, Li, Bing, Yang, Meng-Hang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446656/ https://www.ncbi.nlm.nih.gov/pubmed/30913205 http://dx.doi.org/10.12659/MSM.913091 |
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