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Arsenic Trioxide Inhibits the Metastasis of Small Cell Lung Cancer by Blocking Calcineurin-Nuclear Factor of Activated T Cells (NFAT) Signaling

BACKGROUND: The inhibitory effect of arsenic trioxide (As(2)O(3)) on lung cancer has been reported in some preclinical studies. However, its effect on small cell lung cancer (SCLC) has been poorly explored. Calcineurin and its substrate, nuclear factor of activated T cells (NFAT), mediate the downst...

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Detalles Bibliográficos
Autores principales: Zheng, Jin-Cheng, Chang, Ke-Jie, Jin, Yu-Xiang, Zhao, Xue-Wei, Li, Bing, Yang, Meng-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446656/
https://www.ncbi.nlm.nih.gov/pubmed/30913205
http://dx.doi.org/10.12659/MSM.913091

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