Endocrine Manifestations of Von Hippel–Landau Disease

Von Hippel–Lindau (VHL) disease is an autosomal dominant disorder characterized by various endocrine, nonendocrine, benign, and malignant tumors in various organs. VHL tumor suppressor gene, located on short arm of chromosome 3 is responsible for this. Pheochromocytoma (PCC) is one of the important...

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Autores principales: Pradhan, Roma, George, Nelson, Mandal, Kaushik, Agarwal, Amit, Gupta, Sushil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446673/
https://www.ncbi.nlm.nih.gov/pubmed/31016171
http://dx.doi.org/10.4103/ijem.IJEM_252_18
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author Pradhan, Roma
George, Nelson
Mandal, Kaushik
Agarwal, Amit
Gupta, Sushil K.
author_facet Pradhan, Roma
George, Nelson
Mandal, Kaushik
Agarwal, Amit
Gupta, Sushil K.
author_sort Pradhan, Roma
collection PubMed
description Von Hippel–Lindau (VHL) disease is an autosomal dominant disorder characterized by various endocrine, nonendocrine, benign, and malignant tumors in various organs. VHL tumor suppressor gene, located on short arm of chromosome 3 is responsible for this. Pheochromocytoma (PCC) is one of the important endocrine manifestations that needs to be ruled out in case of VHL suspicion. In this review, we summarize the endocrine manifestations of VHL disease and their management while giving case history of five such cases.
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spelling pubmed-64466732019-04-23 Endocrine Manifestations of Von Hippel–Landau Disease Pradhan, Roma George, Nelson Mandal, Kaushik Agarwal, Amit Gupta, Sushil K. Indian J Endocrinol Metab Review Article Von Hippel–Lindau (VHL) disease is an autosomal dominant disorder characterized by various endocrine, nonendocrine, benign, and malignant tumors in various organs. VHL tumor suppressor gene, located on short arm of chromosome 3 is responsible for this. Pheochromocytoma (PCC) is one of the important endocrine manifestations that needs to be ruled out in case of VHL suspicion. In this review, we summarize the endocrine manifestations of VHL disease and their management while giving case history of five such cases. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6446673/ /pubmed/31016171 http://dx.doi.org/10.4103/ijem.IJEM_252_18 Text en Copyright: © 2019 Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Pradhan, Roma
George, Nelson
Mandal, Kaushik
Agarwal, Amit
Gupta, Sushil K.
Endocrine Manifestations of Von Hippel–Landau Disease
title Endocrine Manifestations of Von Hippel–Landau Disease
title_full Endocrine Manifestations of Von Hippel–Landau Disease
title_fullStr Endocrine Manifestations of Von Hippel–Landau Disease
title_full_unstemmed Endocrine Manifestations of Von Hippel–Landau Disease
title_short Endocrine Manifestations of Von Hippel–Landau Disease
title_sort endocrine manifestations of von hippel–landau disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446673/
https://www.ncbi.nlm.nih.gov/pubmed/31016171
http://dx.doi.org/10.4103/ijem.IJEM_252_18
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AT agarwalamit endocrinemanifestationsofvonhippellandaudisease
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