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Structure, function, and regulation of mitofusin‐2 in health and disease

Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to regulate their shape, size, number, and bioenergetic function. Mitofusins (Mfn1/2), optic atrophy 1 (OPA1), and dynamin‐related protein 1 (Drp1), are key regulators of mitochondrial fusion and fission. Mutations...

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Detalles Bibliográficos
Autores principales:	Chandhok, Gursimran, Lazarou, Michael, Neumann, Brent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446723/ https://www.ncbi.nlm.nih.gov/pubmed/29068134 http://dx.doi.org/10.1111/brv.12378

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