Sulfur Dioxide Activates Cl(-)/HCO(3)(-) Exchanger via Sulphenylating AE2 to Reduce Intracellular pH in Vascular Smooth Muscle Cells

Sulfur dioxide (SO(2)) is a colorless and irritating gas. Recent studies indicate that SO(2) acts as the gas signal molecule and inhibits vascular smooth muscle cell (VSMC) proliferation. Cell proliferation depends on intracellular pH (pH(i)). Transmembrane cystein mutation of Na(+)- independent Cl(...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Wang, Xiuli, Chen, Selena, Tian, Xiaoyu, Zhang, Lulu, Huang, Yaqian, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446831/
https://www.ncbi.nlm.nih.gov/pubmed/30971931
http://dx.doi.org/10.3389/fphar.2019.00313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446831/
https://www.ncbi.nlm.nih.gov/pubmed/30971931
http://dx.doi.org/10.3389/fphar.2019.00313

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