Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering

Lipid droplets (LDs) are hubs for lipid metabolism that form membrane contact sites with multiple organelles. In this issue, Hariri et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808119) reveal the functions of Mdm1-mediated endoplasmic reticulum (ER)–LD tethering in yeast and Datta et a...

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Detalles Bibliográficos
Autores principales: Nguyen, Truc B., Olzmann, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446839/
https://www.ncbi.nlm.nih.gov/pubmed/30886057
http://dx.doi.org/10.1083/jcb.201902160
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author Nguyen, Truc B.
Olzmann, James A.
author_facet Nguyen, Truc B.
Olzmann, James A.
author_sort Nguyen, Truc B.
collection PubMed
description Lipid droplets (LDs) are hubs for lipid metabolism that form membrane contact sites with multiple organelles. In this issue, Hariri et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808119) reveal the functions of Mdm1-mediated endoplasmic reticulum (ER)–LD tethering in yeast and Datta et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808133) identify a role for the Mdm1 orthologue, Snx14, as an ER–LD tether that regulates lipid metabolism in human cells.
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spelling pubmed-64468392019-10-01 Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering Nguyen, Truc B. Olzmann, James A. J Cell Biol Commentaries Lipid droplets (LDs) are hubs for lipid metabolism that form membrane contact sites with multiple organelles. In this issue, Hariri et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808119) reveal the functions of Mdm1-mediated endoplasmic reticulum (ER)–LD tethering in yeast and Datta et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808133) identify a role for the Mdm1 orthologue, Snx14, as an ER–LD tether that regulates lipid metabolism in human cells. Rockefeller University Press 2019-04-01 2019-03-18 /pmc/articles/PMC6446839/ /pubmed/30886057 http://dx.doi.org/10.1083/jcb.201902160 Text en © 2019 Nguyen and Olzmann http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Nguyen, Truc B.
Olzmann, James A.
Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title_full Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title_fullStr Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title_full_unstemmed Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title_short Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
title_sort getting a handle on lipid droplets: insights into er–lipid droplet tethering
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446839/
https://www.ncbi.nlm.nih.gov/pubmed/30886057
http://dx.doi.org/10.1083/jcb.201902160
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