No chromosome left behind: The importance of metaphase alignment for mitotic fidelity

Chromosome alignment is a hallmark of mitosis in metazoans, but the physiological relevance of this orderly behavior has remained unclear. In this issue, Fonseca et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807228) show that chromosome alignment ensures mitotic fidelity by promoting in...

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Detalles Bibliográficos
Autores principales: Orr, Bernardo, Maiato, Helder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446845/
https://www.ncbi.nlm.nih.gov/pubmed/30858193
http://dx.doi.org/10.1083/jcb.201902041
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author Orr, Bernardo
Maiato, Helder
author_facet Orr, Bernardo
Maiato, Helder
author_sort Orr, Bernardo
collection PubMed
description Chromosome alignment is a hallmark of mitosis in metazoans, but the physiological relevance of this orderly behavior has remained unclear. In this issue, Fonseca et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807228) show that chromosome alignment ensures mitotic fidelity by promoting interchromosomal compaction during anaphase.
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spelling pubmed-64468452019-10-01 No chromosome left behind: The importance of metaphase alignment for mitotic fidelity Orr, Bernardo Maiato, Helder J Cell Biol Commentaries Chromosome alignment is a hallmark of mitosis in metazoans, but the physiological relevance of this orderly behavior has remained unclear. In this issue, Fonseca et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807228) show that chromosome alignment ensures mitotic fidelity by promoting interchromosomal compaction during anaphase. Rockefeller University Press 2019-04-01 2019-03-11 /pmc/articles/PMC6446845/ /pubmed/30858193 http://dx.doi.org/10.1083/jcb.201902041 Text en © 2019 Orr and Maiato http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Orr, Bernardo
Maiato, Helder
No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title_full No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title_fullStr No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title_full_unstemmed No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title_short No chromosome left behind: The importance of metaphase alignment for mitotic fidelity
title_sort no chromosome left behind: the importance of metaphase alignment for mitotic fidelity
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446845/
https://www.ncbi.nlm.nih.gov/pubmed/30858193
http://dx.doi.org/10.1083/jcb.201902041
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