Enabling migration by moderation: YAP/TAZ are essential for persistent migration

Persistent cell migration plays a crucial role in physiological processes, but its underlying mechanisms of regulation remain unclear. Mason et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806065) show that YAP/TAZ limit cytoskeletal tension, which is essential for persistent (but not ini...

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Detalles Bibliográficos
Autores principales: Nair, Praful R., Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446847/
https://www.ncbi.nlm.nih.gov/pubmed/30872360
http://dx.doi.org/10.1083/jcb.201902035
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author Nair, Praful R.
Wirtz, Denis
author_facet Nair, Praful R.
Wirtz, Denis
author_sort Nair, Praful R.
collection PubMed
description Persistent cell migration plays a crucial role in physiological processes, but its underlying mechanisms of regulation remain unclear. Mason et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806065) show that YAP/TAZ limit cytoskeletal tension, which is essential for persistent (but not initiation of) cell migration. Potential implications of this study range from embryonic development to metastasis.
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spelling pubmed-64468472019-10-01 Enabling migration by moderation: YAP/TAZ are essential for persistent migration Nair, Praful R. Wirtz, Denis J Cell Biol Commentaries Persistent cell migration plays a crucial role in physiological processes, but its underlying mechanisms of regulation remain unclear. Mason et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806065) show that YAP/TAZ limit cytoskeletal tension, which is essential for persistent (but not initiation of) cell migration. Potential implications of this study range from embryonic development to metastasis. Rockefeller University Press 2019-04-01 2019-03-14 /pmc/articles/PMC6446847/ /pubmed/30872360 http://dx.doi.org/10.1083/jcb.201902035 Text en © 2019 Nair and Wirtz http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Nair, Praful R.
Wirtz, Denis
Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title_full Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title_fullStr Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title_full_unstemmed Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title_short Enabling migration by moderation: YAP/TAZ are essential for persistent migration
title_sort enabling migration by moderation: yap/taz are essential for persistent migration
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446847/
https://www.ncbi.nlm.nih.gov/pubmed/30872360
http://dx.doi.org/10.1083/jcb.201902035
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