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The long and short of membrane curvature sensing by septins

Septin proteins form hetero-oligomers that associate with membranes of specific curvatures, but the mechanism is unknown. In this issue, Cannon et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807211) identify a single amphipathic helix that is necessary and sufficient for membrane curvatu...

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Detalles Bibliográficos
Autor principal: McMurray, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446849/
https://www.ncbi.nlm.nih.gov/pubmed/30890557
http://dx.doi.org/10.1083/jcb.201903045
Descripción
Sumario:Septin proteins form hetero-oligomers that associate with membranes of specific curvatures, but the mechanism is unknown. In this issue, Cannon et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807211) identify a single amphipathic helix that is necessary and sufficient for membrane curvature sensing by septins.