Cargando…

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER–mitochondria contacts

Coenzyme Q (CoQ) lipids are ancient electron carriers that, in eukaryotes, function in the mitochondrial respiratory chain. In mitochondria, CoQ lipids are built by an inner membrane–associated, multicomponent, biosynthetic pathway via successive steps of isoprenyl tail polymerization, 4-hydroxybenz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Subramanian, Kelly, Jochem, Adam, Le Vasseur, Maxence, Lewis, Samantha, Paulson, Brett R., Reddy, Thiruchelvi R., Russell, Jason D., Coon, Joshua J., Pagliarini, David J., Nunnari, Jodi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446851/ https://www.ncbi.nlm.nih.gov/pubmed/30674579 http://dx.doi.org/10.1083/jcb.201808044

Ejemplares similares

Defining intermediates and redundancies in coenzyme Q precursor biosynthesis
por: Robinson, Kyle P., et al.
Publicado: (2021)

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts
por: Murley, Andrew, et al.
Publicado: (2015)

Pannexin 2 Localizes at ER-Mitochondria Contact Sites
por: Le Vasseur, Maxence, et al.
Publicado: (2019)

PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
por: Elbaz-Alon, Yael, et al.
Publicado: (2020)

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
por: Murley, Andrew, et al.
Publicado: (2013)

The “sweet” side of ER-mitochondria contact sites
por: Demetriadou, Anthi, et al.
Publicado: (2017)

Role of Mitochondria–ER Contact Sites in Mitophagy
por: Rühmkorf, Alina, et al.
Publicado: (2023)

GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells
por: Besprozvannaya, Marina, et al.
Publicado: (2018)

Cellular senescence links mitochondria-ER contacts and aging
por: Ziegler, Dorian V., et al.
Publicado: (2021)

Serine palmitoyltransferase assembles at ER–mitochondria contact sites
por: Aaltonen, Mari J, et al.
Publicado: (2021)

The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis
por: Labbé, Katherine, et al.
Publicado: (2021)

Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism
por: Ma, Xiaowen, et al.
Publicado: (2021)

ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis
por: English, Alyssa M., et al.
Publicado: (2020)

β2-adrenergic receptor regulates ER-mitochondria contacts
por: Lim, Youngshin, et al.
Publicado: (2021)

The Interplay of Microtubules with Mitochondria–ER Contact Sites (MERCs) in Glioblastoma
por: Grespi, Francesca, et al.
Publicado: (2022)

ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
por: Steffen, Janos, et al.
Publicado: (2018)

The ER protein Creld regulates ER-mitochondria contact dynamics and respiratory complex 1 activity
por: Paradis, Marie, et al.
Publicado: (2022)

Mitochondria and Coenzyme Q10 in the Pathogenesis of Preeclampsia
por: Teran, Enrique, et al.
Publicado: (2018)

Metabolic Targets of Coenzyme Q10 in Mitochondria
por: Hidalgo-Gutiérrez, Agustín, et al.
Publicado: (2021)

Protein Localization at Mitochondria-ER Contact Sites in Basal and Stress Conditions
por: Ilacqua, Nicolò, et al.
Publicado: (2017)

Perspective: Mitochondria-ER Contacts in Metabolic Cellular Stress Assessed by Microscopy
por: Stacchiotti, Alessandra, et al.
Publicado: (2018)

ER–Mitochondria Contacts and Insulin Resistance Modulation through Exercise Intervention
por: Sun, Yi, et al.
Publicado: (2020)

ER–Mitochondria Contact Sites Reporters: Strengths and Weaknesses of the Available Approaches
por: Giamogante, Flavia, et al.
Publicado: (2020)

Mitochondria as biosynthetic factories for cancer proliferation
por: Ahn, Christopher S, et al.
Publicado: (2015)

Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites
por: John Peter, Arun T., et al.
Publicado: (2017)

UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae
por: Kemmerer, Zachary A., et al.
Publicado: (2021)

Membrane contact site detection (MCS-DETECT) reveals dual control of rough mitochondria–ER contacts
por: Cardoen, Ben, et al.
Publicado: (2023)

Functional Conservation of Coenzyme Q Biosynthetic Genes among Yeasts, Plants, and Humans
por: Hayashi, Kazuhiro, et al.
Publicado: (2014)

ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein
por: Szabo, Leonora, et al.
Publicado: (2023)

Molecular Regulations of FUNDC1 at ER-Mitochondria Contacts Under Hypoxic Stress
por: Zhang, Yi, et al.
Publicado: (2022)

MITOL prevents ER stress‐induced apoptosis by IRE1α ubiquitylation at ER–mitochondria contact sites
por: Takeda, Keisuke, et al.
Publicado: (2019)

Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization
por: Choi, Gee Euhn, et al.
Publicado: (2018)

ER exit sites are physical and functional core autophagosome biogenesis components
por: Graef, Martin, et al.
Publicado: (2013)

Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
por: Ziegler, Dorian V., et al.
Publicado: (2021)

Systems modeling predicts that mitochondria ER contact sites regulate the postsynaptic energy landscape
por: Leung, A., et al.
Publicado: (2021)

α-Synuclein Interactions in Mitochondria-ER Contacts: A Possible Role in Parkinson's Disease
por: Erustes, Adolfo Garcia, et al.
Publicado: (2022)

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells
por: Le Vasseur, Maxence, et al.
Publicado: (2021)

Interactome Analysis of the ER Stress Sensor Perk Uncovers Key Components of ER-Mitochondria Contact Sites and Ca(2+) Signalling
por: Sassano, Maria Livia, et al.
Publicado: (2021)

Mitofusin‐2 knockdown increases ER–mitochondria contact and decreases amyloid β‐peptide production
por: Leal, Nuno Santos, et al.
Publicado: (2016)

ER–Mitochondria contact sites: A new regulator of cellular calcium flux comes into play
por: Krols, Michiel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_01v91t4pnh9lnkjb11s8gkpr84