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Dual roles of EZH2 in acute myeloid leukemia
In this issue of JEM, Basheer et al. (https://doi.org/10.1084/jem.20181276) describe opposing roles of the epigenetic regulator Ezh2 during initiation and maintenance of acute myeloid leukemia (AML). Ezh2 was found to have tumor suppressive and oncogenic functions in different phases of the same mal...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446873/ https://www.ncbi.nlm.nih.gov/pubmed/30890555 http://dx.doi.org/10.1084/jem.20190250 |
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author | Skoda, Radek C. Schwaller, Juerg |
author_facet | Skoda, Radek C. Schwaller, Juerg |
author_sort | Skoda, Radek C. |
collection | PubMed |
description | In this issue of JEM, Basheer et al. (https://doi.org/10.1084/jem.20181276) describe opposing roles of the epigenetic regulator Ezh2 during initiation and maintenance of acute myeloid leukemia (AML). Ezh2 was found to have tumor suppressive and oncogenic functions in different phases of the same malignancy. |
format | Online Article Text |
id | pubmed-6446873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-64468732019-10-01 Dual roles of EZH2 in acute myeloid leukemia Skoda, Radek C. Schwaller, Juerg J Exp Med News In this issue of JEM, Basheer et al. (https://doi.org/10.1084/jem.20181276) describe opposing roles of the epigenetic regulator Ezh2 during initiation and maintenance of acute myeloid leukemia (AML). Ezh2 was found to have tumor suppressive and oncogenic functions in different phases of the same malignancy. Rockefeller University Press 2019-04-01 2019-03-19 /pmc/articles/PMC6446873/ /pubmed/30890555 http://dx.doi.org/10.1084/jem.20190250 Text en © 2019 Skoda and Schwaller http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | News Skoda, Radek C. Schwaller, Juerg Dual roles of EZH2 in acute myeloid leukemia |
title | Dual roles of EZH2 in acute myeloid leukemia |
title_full | Dual roles of EZH2 in acute myeloid leukemia |
title_fullStr | Dual roles of EZH2 in acute myeloid leukemia |
title_full_unstemmed | Dual roles of EZH2 in acute myeloid leukemia |
title_short | Dual roles of EZH2 in acute myeloid leukemia |
title_sort | dual roles of ezh2 in acute myeloid leukemia |
topic | News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446873/ https://www.ncbi.nlm.nih.gov/pubmed/30890555 http://dx.doi.org/10.1084/jem.20190250 |
work_keys_str_mv | AT skodaradekc dualrolesofezh2inacutemyeloidleukemia AT schwallerjuerg dualrolesofezh2inacutemyeloidleukemia |