Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors

Current models propose that group 2 innate lymphoid cells (ILC2s) are generated in the bone marrow. Here, we demonstrate that subsets of these cells can differentiate from multipotent progenitors and committed T cell precursors in the thymus, both in vivo and in vitro. These thymic ILC2s exit the th...

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Detalles Bibliográficos
Autores principales: Qian, Liangyue, Bajana, Sandra, Georgescu, Constantin, Peng, Vincent, Wang, Hong-Cheng, Adrianto, Indra, Colonna, Marco, Alberola-Ila, Jose, Wren, Jonathan D., Sun, Xiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446881/
https://www.ncbi.nlm.nih.gov/pubmed/30898894
http://dx.doi.org/10.1084/jem.20182100

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