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Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors
Current models propose that group 2 innate lymphoid cells (ILC2s) are generated in the bone marrow. Here, we demonstrate that subsets of these cells can differentiate from multipotent progenitors and committed T cell precursors in the thymus, both in vivo and in vitro. These thymic ILC2s exit the th...
Autores principales: | Qian, Liangyue, Bajana, Sandra, Georgescu, Constantin, Peng, Vincent, Wang, Hong-Cheng, Adrianto, Indra, Colonna, Marco, Alberola-Ila, Jose, Wren, Jonathan D., Sun, Xiao-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446881/ https://www.ncbi.nlm.nih.gov/pubmed/30898894 http://dx.doi.org/10.1084/jem.20182100 |
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